Table 2 Work characterization curve (ROC) analysis of subjects with hepatocellular carcinoma
Markers | Cut-off values | AUC(95%CI) | Sensitivity(%) (95%CI) | Specificity(%) (95%CI) | Youden Index | FPR(%) | FNR(%) |
|---|---|---|---|---|---|---|---|
AFP-L3 | 17.28 ng/mL | 0.849(0.804–0.893) | 77.4(84.5–87.3) | 87.0(50.1–60.7) | 0.644 | 13 | 22.6 |
PIVKA-II | 61.67 μg/L | 0.582(0.517–0.647) | 41.2(18.3–22.0) | 88.0(64.3–71.4) | 0.292 | 12 | 58.8 |
D-Dimer | 0.600 mg/L | 0.687(0.622–0.752) | 70.4(64.3–71.4) | 63.0(50.4–59.7) | 0.334 | 37 | 29.6 |
FDP | 2.35 mg/L | 0.776(0.719–0.833) | 92.5(34.8–46.8) | 52.0(74.7–84.9) | 0.445 | 48 | 7.5 |
CHI3L1 | 58.575 μg/L | 0.923(0.890–0.957) | 84.9(94.1–96.2) | 89.0(46.9–57.2) | 0.739 | 11 | 15.1 |