Fig. 1

Effect of oxygen concentration on viral packaging and transduction efficiency. (A) Fluorescence images of 293T cells packaged under normoxia (N) or hypoxia (L). (B, C, D) Fluorescence images, flow cytometry plots, and quantification of K562 cells transduced under normoxia (N) or hypoxia (L). (E) qPCR analysis of viral genome integration. n = 3, *p < 0.05; **p < 0.01; ***p < 0.001, data are presented as the mean ± standard deviation