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Fig. 5 | BMC Biotechnology

Fig. 5

From: Parabacteroides distasonis promotes CXCL9 secretion of tumor-associated macrophages and enhances CD8+T cell activity to trigger anti-tumor immunity against anti-PD-1 treatment in non-small cell lung cancer mice

Fig. 5

P. distasonis enhanced TAM-mediated CD8+T cell activity. (A and B) Flow cytometry analysis of positive proportion of GZMB and IFN-γ in CD8+T cells in mouse tumor tissue. *P < 0.05 vs. PBS. (C and D) Flow cytometry determination of proportion of GZMB+T and IFN-γ+T cells in primary CD8+T cells of spleen. (E) ELISA detection of secretion of IFN-γ, TNF-α, Perforin and GZMB in supernatant of primary CD8+T cells of spleen. *P < 0.05 vs. Control

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BMC Biotechnology

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