Fig. 3

Cell viability in kidney cancer spheroids treated or not with collagen I. 786-O (A) or WT-CLS1 (B) were cultured as spheroids in absence or presence of collagen I. A CellTiter-Glo 3D assay was performed on one to five cultured spheroids to measure cell viability. For each independent experiment, data are normalized to one spheroid cultured without collagen I. The figure presented is the mean +/- SEM of 3 to 4 independent experiments (n = 3 for 786-O and n = 4 for WT-CLS1 cells), Wilcoxon-Mann-Whitney test