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Table 3 Changes in the level of serum AST, and ALT of EAC tumor-bearing mice receiving CP, TQ, AuNPs, AgNPs AuNPs/TQ, AgNPs/TQ, AuNPs/TQ + CP, and AgNPs/TQ + CP

From: Impacts of loading thymoquinone to gold or silver nanoparticles on the efficacy of anti-tumor treatments in breast cancer with or without chemotherapeutic cisplatin

Groups

ALT (U/L)

AST (U/L)

Naïve

87.33 ± 7.22

57.67 ± 10.11

PBS

45.0 ± 2.31a

65.00 ± 3.21

CP

29.0 ± 0.58a, b

56.33 ± 0.88

TQ

16.33 ± 0.88a, b

41.00 ± 5.86

AuNPs

29.0 ± 0.58a, b

84.00 ± 8.33

AgNPs

26.67 ± 4.91a, b

110.00 ± 10.41a, b,c

AuNPs/TQ

12.33 ± 0.33a, b,c

45.00 ± 2.65

AgNPs/TQ

22.67 ± 5.36a, b

60.33 ± 9.06

AuNPs/TQ + CP

22.0 ± 3.61a, b

90.00 ± 10.41a, c

AgNPs/TQ + CP

28.67 ± 4.06a, b

56.00 ± 2.65

  1. Data are postulated as mean ± SE (n = 5). A statistically significant difference between the groups was established at P < 0.05. a, b,c indicate statistically significant differences, when compared to the naïve mice group (a), EAC tumor-bearing mice receiving PBS (b), EAC tumor-bearing receiving CP (c)