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Table 10 HFB4 normal human skin cell line viability affected by various concentrations of pyrazole 3b

From: Antifungal activity and biocompatibility assessment with molecular docking and dynamic simulations of new pyrazole derivatives

ID

µg/ml

O.D

Mean O.D

±SE

Viability %

Toxicity %

IC50 ± SD

HFB4

——–

0.568

0.561

0.566

0.565000

0.002082

100

0

µg/ml

3b

1000

0.569

0.560

0.560

0.563000

0.003000

99.23303835

0.766961652

—–

500

0.565

0.566

0.562

0.564333

0.001202

99.64601770

0.353982301

250

0.564

0.567

0.562

0.564333

0.001453

99.76401180

0.235988201

125

0.563

0.567

0.561

0.563667

0.001764

99.88200590

0.117994100

62.5

0.561

0.567

0.564

0.564000

0.001732

99.82300885

0.117994100

31.25

0.558

0.564

0.560

0.560667

0.001764

99.88200590

0.176991150