Table 2 Experimental design matrix with ANOVA for cubic model to relative contributions and potential interactions among the mixture components (oregano, moringa and cinnamon) influencing the inhibition zone diameter

Model

51.74

9

5.75

100.83

< 0.0001

significant

⁽¹⁾Linear Mixture

10.47

2

5.23

91.79

< 0.0001

AB

15.06

1

15.06

264.13

< 0.0001

AC

9.85

1

9.85

172.68

< 0.0001

BC

0.8661

1

0.8661

15.19

0.0080

ABC

14.24

1

14.24

249.74

< 0.0001

AB(A-B)

7.34

1

7.34

128.66

< 0.0001

AC(A-C)

9.13

1

9.13

160.10

< 0.0001

BC(B-C)

0.2263

1

0.2263

3.97

0.0934

Std. Dev.

0.2388

R²

0.9934

Std. Dev.

0.2388

Mean

3.38

Adjusted R²

0.9836

Mean

3.38

C.V. %

7.07

Predicted R²

0.7452

C.V. %

7.07