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Table 1 Antibacterial activity of phage, chitosan and phage encapsulated CS-NPs against different strains of Enterobacter cloacae

From: Chitosan nano-formulation enhances stability and bactericidal activity of the lytic phage HK6

Enterobacter cloacae Strains

HK6

Chitosan only

Phage encapsulated in CS-NPs

Antibiotic resistance [13]

EC3

+

-

+

AMP, AMC, CAZ, CXT

EC 4

-

-

-

AMP, AMC. CXT

EC 7

+

+

++

AMP, AMC, CAZ, CXT

EC 10

-

+

+

AMP, AMC. CXT

EC 11

+

+

++

AMP, AMC, CAZ, CXT

EC 12

-

-

-

AMP, AMC. CXT

EC 13

-

+

+

AMP, AMC. CXT

EC 21

+

+

++

AMP, AMC. CXT

EC 25

+

+

+

AMP, AMC, CAZ, CXT, CIP, SXT

EC 26

-

-

-

AMP, AMC. CXT

EC 29

+

-

+

AMP, AMC, CAZ, CXT, CIP

EC 34

+

+

++

AMP, AMC, CAZ, CXT

  1. (-) no zone of inhibition
  2. (+) zone of inhibition with diameter from 5–7 mm
  3. (++) zone of inhibition with diameter from 7–11 mm
  4. AMP Ampicillin, AMC Amoxycillin – clavulanic, CAZ Ceftazidime, CXT Ceftriaxone, CIP Ciprofloxacin, SXT Sulfamethoxazole-trimethoprim