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Table 6 Phenolic contents of Hypericum Spectabile

From: Biological activities of Hypericum spectabile extract optimized using artificial neural network combined with genetic algorithm application

Phenolic compounds

Ret. time

Values (mg/kg)

Potential health benefit

Fumaric acid

0.859

1249.53 ± 0.82

Anti-inflammatory and analgesic activity [38]

Gallic acid

1.483

5196.31 ± 0.86

Anticancer activity [39]

Protocatechuic acid

2.060

2097.95 ± 1.14

Antioxidant and antihyperlipidaemic activity [40]

4-hydroxybenzoic acid

2.550

698.61 ± 1.11

Antiproliferative and proapoptotic activity [41]

Caffeic acid

2.850

3549.96 ± 1.38

Anti-hepatitis B virus activity [41]

2-hydoxycinnamic acid

3.553

546.50 ± 0.75

Antioxidant activity [42]

Quercetin

4.000

2587.52 ± 1.24

Anti-inflammatory activity [43]

Kaempferol

4.222

390.91 ± 0.73

Antitumor, antioxidant and anti-inflammatory [44]