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Table 2 Univariate and multivariate analyses for HBV-specific T cells/2*10^5 PBMC in CHB patients

From: Optimization of culture conditions for HBV-specific T cell expansion in vitro from chronically infected patients

 

HBV-specific T cells/2*10^5 PBMC (n = 133)

r

p

β

p

Gender (female)

0.013

0.855

  

Age (years)

0.064

0.463

  

ALT (U/L)

0.079

0.369

  

AST (U/L)

0.080

0.359

  

γ-GGT (U/L)

0.067

0.441

  

TP (g/L)

-0.143

0.114

  

ALB (g/L)

-0.357

< 0.0001

-0.348

0.003

GLB (g/L)

0.118

0.190

  

WBC (10^9/L)

-0.185

0.033

0.081

0.859

NEUT (10^9/L)

-0.195

0.025

-0.230

0.540

LYM (10^9/L)

-0.201

0.020

-0.176

0.369

HBeAg-positive

-0.250

0.004

-0.395

< 0.001

HBsAg (IU/ml)

-0.420

< 0.0001

-0.408

0.008

HBV DNA > 100 (IU/ml)

0.070

0.424

  

HBcAb (IU/ml)

-0.063

0.498

  

Treatment-naive

0.683

0.036

  

Treatment

    

NAs

reference

  

IFN

0.302

0.007

-0.183

0.268

Treatment-time (month)

-0.245

0.032

-0.056

0.664

  1. Note: In two-variable correlation analysis, Spearman’s rank correlation was used for two continuous variables, and Kendall’s rank correlation was used if one of the variables was discontinuous; the r values represent the correlation coefficients. In multiple linear regression analysis, the stepwise regression was used to determine the variables in the regression equation; the β values represent the standardized regression coefficients
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BMC Biotechnology

ISSN: 1472-6750

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