Table 3 The calculated kinetic parameters of Sunitinib malate release according to Higuchi and Korsmeyer-Peppas models [28]
Higuchi model | Korsmeyer-Peppas model | ||||||
|---|---|---|---|---|---|---|---|
KH | R2 | N | KKP | R2 | |||
Hyd (0 wt%) | pH = 5.5 | 9.78 | 0.96 | 0.89 | 1.44 | 0.99 | |
pH = 7.4 | 20.26 | 0.95 | 0.75 | 16.97 | 0.98 | ||
Hyd/Cloisite 30B (2 wt%) | pH = 5.5 | 8.76 | 0.97 | 0.68 | 2.06 | 0.99 | |
pH = 7.4 | 15.65 | 0.96 | 0.53 | 14.24 | 0.98 | ||
Hyd/Cloisite 30B (4 wt%) | pH = 5.5 | 7.23 | 0.97 | 0.51 | 2.39 | 0.99 | |
pH = 7.4 | 15.01 | 0.94 | 0.48 | 13.94 | 0.99 | ||
Hyd/Cloisite 30B (6 wt%) | pH = 5.5 | 2.69 | 0.97 | 0.38 | 6.97 | 0.99 | |
pH = 7.4 | 12.011 | 0.95 | 0.28 | 8.80 | 0.99 | ||
Hyd/Cloisite 30B (8 wt%) | pH = 5.5 | 4.73 | 0.96 | 0.41 | 2.96 | 0.99 | |
pH = 7.4 | 14.53 | 0.95 | 0.36 | 12.55 | 0.98 | ||
Hyd/Cloisite 30B (10 wt%) | pH = 5.5 | 2.73 | 0.93 | 0.39 | 5.81 | 0.99 | |
pH = 7.4 | 13.93 | 0.97 | 0.31 | 11.84 | 0.98 | ||