Fig. 6

Effect on M2 macrophage after transfection with sh-PAR-1 and pcDNA3.1-PAR-1. A ELISA measured the concentrations of IL-10, TGF-β, Arg, IL-6, TNF-α, and IL-1β. B Expression of IL-10, TGF-β, Arg, IL-6, TNF-α, and IL-1β was obtained by RT-qPCR. One-way ANOVA was used for comparison between multiple groups. n.s, not significant, ****P < 0.0001, ***P < 0.001, **P < 0.01 and *P < 0.05