Fig. 1

Macrophage polarisation and PAR-1 expression in clinical samples. A CD68 + pSTAT1 + and CD163 + CMAF + were detected by flow cytometry. The supporting images of the gating strategy are shown in Supplementary Fig. S1A. B RT-qPCR for the expression of IL-6, TNF-α, IL-1β, IL-10, TGF-β and Arg. C Immunohistochemical (IHC) detection of PAR-1 expression in DLBCL tissue and adjacent tissue, scale bar = 50 μm, n = 5. A T-test was used to compare the two groups. ****P < 0.0001