Table 2 The final HTL epitopes for the MEV construction
From: Design of a novel multi-epitope vaccine against Marburg virus using immunoinformatics studies
Allele | Final HTL Epitopes | Protein | Antigenicity | Allergenicity |
|---|---|---|---|---|
HLA-DRB1*15:01, HLA-DRB3*02:02, HLA-DPA1*02:01/DPB1*05:01, HLA-DQA1*01:02/DQB1*06:02, HLA-DPA1*02:01/DPB1*01:01, HLA-DPA1*03:01/DPB1*04:02, HLA-DRB1*04:05, HLA-DRB1*12:01, HLA-DPA1*01:03/DPB1*04:01 | 1MASSSNYNTYMQYLNPPPYADHGANQLIPADQLSNQQGITPNYVGDLNLDDQFKGNVCHA60 | VP40 | 0.44 | non-allergen |
HLA-DRB1*11:01, HLA-DRB4*01:01,HLA-DQA1*01:02/DQB1*06:02,HLA-DQA1*01:01/DQB1*05:01, HLA-DRB1*09:01, HLA-DRB5*01:01, HLA-DRB1*01:01, HLA-DRB1*08:02 | 2WDSSYMQQVSEGLMTGKVPIDQVFGANPLEKLYKRRKPKGTVGLQCSPCLMSKAT56 | VP35 | 0.44 | non-allergen |
HLA-DQA1*03:01/DQB1*03:02, HLA-DRB1*12:01, HLA-DRB3*02:02, HLA-DRB1*13:02, HLA-DQA1*05:01/DQB1*02:01, HLA-DRB1*04:05, HLA-DRB1*04:01, HLA-DQA1*03:01/DQB1*03:02, HLA-DRB1*04:05 | 1MKTTCLFISLILIQGIKTLPILEIASNNQPQNVDSVCSGTLQKTEDVHLMGFTLSGQKVADSPLE65 | GP | 0.73 | non-allergen |