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Fig. 3 | BMC Biotechnology

Fig. 3

From: Increased stable integration efficiency in CHO cells through enhanced nuclear localization of Bxb1 serine integrase

Fig. 3

Double and triple NLS variants of Bxb1 integrase. Construct on top shows the configration of the double NLS variants with NLSs at N- and C-terminus. Constructs in the middle and at the bottom illusrate the configuration of Bxb1-NPLCx2 and Bxb1-NPLCx3 variants, respectively. NLS sequences of Bxb1-NPLCx2 and Bxb1-NPLCx3 are separated by a flexible GGGGSGGGGSGS linker (white arrow)

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