Fig. 1

A Arrangement of the HTL and CTL epitopes in the final vaccine construct using different linkers. B B-cell epitopes as predicted by the BCPred server; in the 3D structure of the vaccine, linear B-cell epitopes are presented in magenta, while conformational B-cell epitopes are presented in pink. C Predicting the secondary structure and solubility of the vaccine construct; the results of the PSIPRED server for predicting the secondary structure of the vaccine construct showed 46.86% coils, 38.14% alpha-helices, and 10.35% beta-strands. D Multi-template modeling of the final 3D structure of the vaccine; the relevant elements are depicted in different colors, loops in sky blue, beta-sheets in colored blue, and helices in red